Cancer and Aging Research Group Chemotherapy Toxicity Tool (CARG-TT)
Estimates the risk of severe chemotherapy-related side effects (Grade 3 or greater toxicity) in older cancer patients.
Advice
- This tool should augment, not replace, a comprehensive patient assessment and clinical expertise.
- Use risk estimates to facilitate informed discussions about goals of care and treatment preferences.
- Adjust therapy as needed—this may include chemotherapy dose reduction, the implementation of supportive measures, or opting for less intensive regimens in cases of high toxicity risk.
- Plan for closer monitoring and reassessment over the course of treatment, particularly if the risk of toxicity is moderate to high.
- Reassess risk as patient status changes over time (e.g., after an initial chemo cycle, new comorbidity).