 Critical Issues in the Evaluation and Management of Adult Patients With Suspected Acute Nontraumatic Thoracic Aortic Dissection

Official 2014 guideline from the American College of Emergency Physicians.

Thoracic Aortic Dissection

 Critical Issues in the Evaluation of Adult Patients With Suspected Transient Ischemic Attack in the Emergency Department

Official 2016 guideline from the American College of Emergency Physicians.

Suspected TIA

 Critical Issues in the Initial Evaluation and Management of Patients Presenting to the Emergency Department in Early Pregnancy

Early Pregnancy

Clinical Policy for Well-Appearing Infants and Children Younger Than 2 Years of Age Presenting to the Emergency Department With Fever

Fever in <2 Year Olds

Critical Issues Related to Opioids in Adult Patients Presenting to the Emergency Department

Official 2020 guideline from the American College of Emergency Physicians.

Official 2020 guideline from ACEP.

Opioids

Critical Issues in the Diagnosis and Management of the Adult Psychiatric Patient in the Emergency Department

Official 2017 guideline from the American College of Emergency Physicians.

Psychiatric Patient

Critical Issues in the Evaluation and Management of Adult Out-of-Hospital or Emergency Department Patients Presenting With Severe Agitation

Official 2023 guideline for severe agitation from the American College of Emergency Physicians.

Based on 2023 guideline for severe agitation from ACEP.

Severe Agitation

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning

Official 2025 guideline from the American College of Emergency Physicians.

Carbon Monoxide Poisoning

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache

Official 2019 guideline from the American College of Emergency Physicians.

Headache

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Heart Failure Syndromes

Official 2022 guideline from the American College of Emergency Physicians.

Acute Heart Failure Syndromes

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Suspected Acute Venous Thromboembolic Disease

Official 2018 guideline from the American College of Emergency Physicians.

Acute Venous Thromboembolic Disease

Critical Issues in the Evaluation and Management of Adult Patients in the Emergency Department With Asymptomatic Elevated Blood Pressure

Official 2013 guideline from the American College of Emergency Physicians.

Asymptomatic Hypertension

Critical Issues in the Evaluation and Management of Emergency Department Patients With Suspected Appendicitis

Official 2023 guideline from the American College of Emergency Physicians.

Official 2023 guideline from ACEP.

Appendicitis

Critical Issues in the Evaluation and Management of Emergency Department Patients With Suspected Non-ST-Elevation Acute Coronary Syndromes

Official 2018 guideline from ACEP.

Non-ST Elevation Acute Coronary Syndromes

Critical Issues in the Evaluation of Adult Patients Presenting to the Emergency Department With Acute Blunt Trauma

Based on 2024 guideline for acute blunt trauma from the American College of Emergency Physicians.

Based on 2024 guideline for blunt trauma from ACEP.

Acute Blunt Trauma

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Community-Acquired Pneumonia

Community-Acquired Pneumonia

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Mild Traumatic Brain Injury

Mild TBI

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Seizures

Official 2024 guideline from the American College of Emergency Physicians.

Official 2024 guideline from ACEP.

Seizure

Critical Issues in the Outpatient Management of Adult Patients Presenting to the Emergency Department With Asymptomatic Elevated Blood Pressure

Official 2025 Guideline from the American College of Emergency Physicians.

2025 ACEP Guideline for Outpatient Asymptomatic Elevated BP.

Outpatient Management of Asymptomatic Elevated Blood Pressure

Emergency Department Management of Patients Needing Reperfusion Therapy for Acute ST-Segment Elevation Myocardial Infarction

Reperfusion (STEMI)

Procedural Sedation and Analgesia in the Emergency Department

Procedural Sedation/Analgesia

Use of Thrombolytics for the Management of Acute Ischemic Stroke in the Emergency Department

Thrombolytics in Acute Ischemic Stroke

Acute-on-Chronic Liver Failure

Official guideline from the American College of Gastroenterology.

Alcoholic Liver Disease

Chronic Pancreatitis

Pancreatitis: Chronic

Clinical Use of Esophageal Physiologic Testing

Official guideline of the American College of Gastroenterology.

Esophageal Physiologic Testing

Colorectal Cancer Screening 2021

Colorectal Cancer

Diagnosis and Management of Achalasia

Achalasia

Diagnosis and Management of Barrett’s Esophagus

Official guideline from the American College of Gastroenterology.
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Barrett’s

Diagnosis and Management of Celiac Disease

Official 2023 guideline of the American College of Gastroenterology.

Celiac

Diagnosis and Management of Eosinophilic Esophagitis (EoE)

Official 2025 guideline from the American College of Gastroenterology.

Diagnosis and Management of Gastroesophageal Reflux Disease

GERD

Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

DILI

Diagnosis and Management of Pancreatic Cysts

Pancreatic Cysts

Diagnosis and Management of Small Bowel Bleeding

Small Bowel Bleeding

Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults

Diarrhea

Disorders of the Hepatic and Mesenteric Circulation

Liver: Hepatic and Mesenteric Circulation

Epidemiology, Risk Factors, Patterns of Presentation, Diagnosis, and Management of Colon Ischemia (CI)

Colon Ischemia

Evaluation of Abnormal Liver Chemistries

Abnormal Liver Chemistries

Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes

Hereditary GI Cancer Syndromes

Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile Infections

Official guideline from the American College of Gastroenterology, updated June 2021.

C. diff

Hereditary Hemochromatosis

Hemochromatosis: Hereditary

Liver Disease and Pregnancy

Management of Acute Pancreatitis

Official 2024 guideline from the American College of Gastroenterology.

Pancreatitis

Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period

Acute Gastrointestinal Bleeding

Management of Crohn’s Disease in Adults

Crohn's Disease

Management of Dyspepsia

Dyspepsia

Management of Gastroparesis

Gastroparesis

Management of Irritable Bowel Syndrome

IBS Therapy

Management of Patients With Acute Lower Gastrointestinal Bleeding

LGIB

Nutrition Therapy in the Adult Hospitalized Patient

Nutrition

Preventive Care in Inflammatory Bowel Disease

Preventive Care - IBD

Primary Sclerosing Cholangitis

Small Intestinal Bacterial Overgrowth

SIBO

The Diagnosis and Management of Focal Liver Lesions

Liver: Focal Liver Lesions

Treatment of Helicobacter pylori Infection

H. pylori

Ulcerative Colitis in Adults

Ulcerative Colitis

Updated Diagnosis and Management of Barrett’s Esophagus

Barrett's Esophagus

Upper Gastrointestinal and Ulcer Bleeding

Official guideline from the American College of Gastroenterology, updated May 2021.

Ulcer Bleeding

Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis

2024 Clinical Practice Guideline from the American Gastroenterological Association.

Pharmacological Management of Ulcerative Colitis

Gastrointestinal Evaluation of Iron Deficiency Anemia

Based on guidelines from the American Gastroenterological Association.

Iron Deficiency Anemia

Initial Management of Acute Pancreatitis

Acute Pancreatitis

Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D)

Based on guidelines from the American Gastroenterological Association. Use to evaluate an immunocompetent patient with complaints of "watery" diarrhea of at least 4 weeks duration.

Irritable Bowel Syndrome in Adults (IBS-D)

Management of Acute Diverticulitis

Acute Diverticulitis

Medical Management of Microscopic Colitis

Microscopic Colitis

Pharmacological Management of Irritable Bowel Syndrome With Constipation (IBS-C)

Based on guidelines from the American Gastroenterological Association. Expert content provided by Morgan Allyn Sendzischew Shane, MD, MSCTI.

Irritable Bowel Syndrome With Constipation (IBS-C)

Pharmacological Management of Irritable Bowel Syndrome With Diarrhea (IBS-D)

Irritable Bowel Syndrome With Diarrhea (IBS-D)

Prevention and Treatment of Hepatitis B Virus Reactivation (HBVr) in At-Risk Individuals

2025 Guideline from the American Gastroenterological Association for Hepatits B Virus Reactivation.

HBVr Prevention

Adjuvant Endocrine Therapy for Women With Hormone Receptor-positive Breast Cancer

Based on guidelines from the American Society of Clinical Oncology.

Hormone Receptor-positive Breast Cancer

Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stages I-IIIA Completely Resected Non-small Cell Lung Cancers

Based on guidelines from the American Society of Clinical Oncology and Cancer Care Ontario.

Non-small Cell Lung Cancer

Adjuvant Therapy for Resected Biliary Tract Cancer

Biliary Tract Cancer

Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors

Based on guidelines from the Congress of Neurological Surgeons, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr> and <abbr title="Society for Neuro-Oncology">SNO</abbr>.

Metastatic Brain Tumors

Chemotherapy and Targeted Therapy for Women with HER2-negative (or unknown) Advanced Breast Cancer

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HER2-negative Advanced Breast Cancer

Clinically Localized Prostate Cancer

Based on guidelines from <abbr title="American Urological Association">AUA</abbr>, <abbr title="American Society for Radiation Oncology">ASTRO</abbr>, and <abbr title="Society of Urologic Oncology">SUO</abbr>, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr>.

Based on guidelines from AUA, ASTRO, and SUO.

Prostate Cancer

Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (LA NSCLC)

Based on guidelines from the American Society for Radiation Oncology, also endorsed by ASCO.

Locally Advanced Non-small Cell Lung Cancer

Diabetes Care in the Hospital

Based on guidelines from the American Diabetes Association.

Diabetes Care

Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza

Based on guidelines from the Infectious Diseases Society of America.

Seasonal Influenza

Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer

Based on guidelines from the American Society of Clinical Oncology.

Colon Cancer

Hereditary Colorectal Cancer Syndromes

Based on guidelines from the European Society for Medical Oncology, also endorsed by ASCO.

Hereditary CRC

Initial Diagnostic Work-Up of Acute Leukemia

Based on guidelines from <abbr title="College of American Pathologists">CAP</abbr> and <abbr title="American Society of Hematology">ASH</abbr>, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr>.

Guidelines Summaries