MDCalc

Bacterial Meningitis Score for Children

Rules out bacterial meningitis.

Use in patients aged 29 days to 19 years with CSF WBC ≥10 cells/μL. Do not use if patient is critically ill, recently received antibiotics, has a VP shunt or recent neurosurgery, is immunosuppressed, or has other bacterial infection requiring antibiotics (including Lyme disease).

CSF Gram stain positive
CSF ANC ≥1,000 cells/µL
CSF protein ≥80 mg/dL (800 mg/L)
Peripheral blood ANC ≥10,000 cells/µL
Seizure at (or prior to) initial presentation

Result:

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Management

For patients at very low risk for bacterial meningitis (BMS 0):

  • Consider discharge with close follow-up (ideally within 24–48 hours) and return precautions for family, including new seizure activity, altered mental status, purpuric rash, or other concerning symptoms.
  • Consider a single dose of long-acting antibiotics with good CSF penetration, such as ceftriaxone, prior to discharge.

For patients with at least 1 risk factor for bacterial meningitis or high clinical suspicion (BMS >0):

  • Consider admission for parenteral antibiotics and observation while awaiting CSF culture results.
  • Make sure CSF is sent for culture.
  • Consider continuous monitoring of vital signs and regular neurologic exams.
  • If not previously administered, start empiric broad spectrum antibiotics.
  • Consider expanding antimicrobial coverage:
    • If concern for herpes encephalitis, add acyclovir.
    • If high clinical suspicion for tuberculous meningitis, consult with infectious disease specialist and consider rifAMPin, isoniazid, pyrazinamide, and a fluoroquinolone or aminoglycoside.
  • Consider steroid administration based on clinical presentation, geographic area, and potential risk factors.
Critical Actions
  • Physician gestalt, severity of illness and clinical presentation supersedes the application of the BMS prediction rule.
  • If significant suspicion for bacterial meningitis, err on the side of caution and admit for observation and empiric antibiotics.