MDCalc

Gail Model for Breast Cancer Risk

Estimates risk for breast cancer based on demographic and clinical data.

This calculator includes inputs based on race, which may or may not provide better estimates; this calculator can be run with Race as “Unknown,” but users should know this defaults to the “White” option. Our evidence section reviews some of the issues with Race in this model. Learn more about our approach to addressing race and bias on MDCalc.

The Gail Model is for use in women with no history of breast cancer, DCIS or LCIS. Other tools may be more appropriate for women with known mutations in BRCA1, BRCA2, or other hereditary syndromes associated with breast cancer. See the Evidence section for more information.

years

First menstrual period

First live birth

First-degree relatives with breast cancer

Include only mother, sisters and daughters

Previous breast biopsy

Race/ethnicity

Result:

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Advice

Patients who have an increased risk of developing breast cancer, defined as calculated 5 year risk >1.7%, are candidates for chemoprevention (such as tamoxifen).

Critical Actions

Patients with elevated breast cancer risk (>1.7%) should be referred to a breast surgeon to discuss possible risk reduction interventions.