MDCalc

Simplified Autoimmune Hepatitis (AIH) Score

Diagnoses autoimmune hepatitis.

Use in patients with histological evidence of hepatitis. Do not use in patients with normal histology.

ANA or SMA/F-actin

LKM1 antibody

SLA

IgG

Liver histology

If histology is normal, AIH is not the diagnosis.
Viral hepatitis

Result:

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Advice

AIH is a complex diagnosis partly because there is no anatomic criterion (i.e. ‘gold’) standard. AIH scoring neatly solves this problem by defining the diagnosis. ‘Likely’ scores appear highly reliable.

Management

We are unaware of validated management algorithms using the AIH scores.

Critical Actions

Overlap with multiple hepatic conditions is always a concern to consider despite score findings, and ‘likely’ scores are more predictive than ‘probable’ ones.