Indian Takayasu Clinical Activity Score (ITAS2010)
Differentiates between active and inactive disease in Takayasu arteritis (TAK).
Select a feature only if the abnormality is new (or worsening) within the past 3 months AND ascribed to current active vasculitis.
Advice
- This tool is not intended to replace good clinical judgment and specialist expertise.
- Use as part of a comprehensive evaluation (e.g., physical examination, laboratory data, imaging studies) to guide treatment decisions and monitoring.
Management
The following cutoffs are based on the original study by Misra et al. (2013):
- Inactive disease (score <2): Consider tapering immunosuppressive therapy cautiously.
- Active disease (score ≥2):
- Consider intensifying treatment with corticosteroids, additional immunosuppressants, and/or biologic therapy.
- Evaluate treatment adherence and exclude other conditions that may mimic disease activity.
- Persistent elevation despite treatment may warrant vascular imaging to assess progression and rule out complications.